HitPredict

Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Interactor 2: NACC1 (Q96RE7)
Nucleus accumbens-associated protein 1 (NAC-1) (BTB/POZ domain-containing protein 14B)
Gene: NACC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17699672
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 759 Hs			1 527
+	Hs
		1043281 CUL4A_HUMAN (1-759): 0: 963: 100.00		KLHL3_HUMAN (9-267): 3.35e-63: 218: 17.16
+	Hs
		1042971 CUL4A_HUMAN (1-759): 0: 963: 100.00		KEAP1_HUMAN (3-260): 7.39e-59: 207: 14.66
+	Hs
		1043391 CUL4B_HUMAN (10-759): 0: 927: 82.31		KLH12_HUMAN (10-268): 5.89e-67: 227: 18.63
+	Hs
		1043181 CUL4A_HUMAN (1-759): 0: 963: 100.00		ZBT18_HUMAN (7-218): 1.33e-45: 169: 22.12
+	Hs
		1042981 CUL4A_HUMAN (1-759): 0: 963: 100.00		HIC1_HUMAN (7-293): 1.5e-42: 163: 20.40
+	Hs
		1041712 CUL3_HUMAN (32-759): 0: 814: 38.23		KLH12_HUMAN (10-268): 5.89e-67: 227: 18.63
+	Hs
		307170 CUL3_HUMAN (32-759): 0: 814: 38.23		KLHL2_HUMAN (9-322): 4.22e-63: 218: 15.46
+	Rn
		78189 CUL3_RAT (32-759): 0: 814: 38.36		KLH17_RAT (8-265): 2.01e-62: 217: 15.41
+	Hs
		299515 CUL3_HUMAN (32-759): 0: 814: 38.23		KLH18_HUMAN (1-265): 4.74e-62: 215: 17.58
+	Hs
		312064 CUL3_HUMAN (32-759): 0: 814: 38.23		ZBT7A_HUMAN (1-431): 6.26e-61: 212: 16.86
+	Hs
		1041718 CUL3_HUMAN (32-759): 0: 814: 38.23		KLH26_HUMAN (7-314): 4.14e-60: 210: 16.03
+	Hs
		1041547 CUL3_HUMAN (32-759): 0: 814: 38.23		KEAP1_HUMAN (3-260): 7.39e-59: 207: 14.66
+	Hs
		1041720 CUL3_HUMAN (32-759): 0: 814: 38.23		Q53SE7_HUMAN (21-452): 1.18e-56: 199: 15.27
+	Hs
		781364 CUL3_HUMAN (32-759): 0: 814: 38.23		BCL6_HUMAN (6-350): 2.1e-49: 182: 19.07
+	Hs
		983972 CUL3_HUMAN (32-759): 0: 814: 38.23		ZBT16_HUMAN (4-346): 1.57e-48: 180: 20.52
+	Hs
		1024288 CUL3_HUMAN (32-759): 0: 814: 38.23		ZBT17_HUMAN (7-365): 4.44e-45: 171: 20.89
+	Hs
		157202 CUL3_HUMAN (32-759): 0: 814: 38.23		BACH1_HUMAN (4-263): 1.21e-38: 152: 20.53
+	Hs
		152489 CUL3_HUMAN (32-759): 0: 814: 38.23		ENC1_HUMAN (7-127): 7.15e-39: 151: 28.80
+	Hs
		196609 CUL3_HUMAN (32-759): 0: 814: 38.23		ZBT24_HUMAN (12-223): 1.63e-37: 148: 22.48
+	Hs
		215889 CUL3_HUMAN (32-759): 0: 814: 38.23		ZBT14_HUMAN (1-216): 4.21e-38: 147: 24.03