HitPredict

Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Interactor 2: WDR26 (Q9H7D7)
WD repeat-containing protein 26 (CUL4- and DDB1-associated WDR protein 2) (Myocardial ischemic preconditioning up-regulated protein 2)
Gene: WDR26

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	32235678, 17041588
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 759 Hs			1 661
+	Hs
		1043589 CUL4B_HUMAN (10-759): 0: 927: 82.31		WDR26_HUMAN (28-661): 5.33e-158: 471: 100.00
+	Hs
		1042550 CUL3_HUMAN (32-759): 0: 814: 38.23		WDR26_HUMAN (28-661): 5.33e-158: 471: 100.00
+	Hs
		792982 CUL4A_HUMAN (1-759): 0: 963: 100.00		LIS1_HUMAN (394-661): 1.17e-77: 255: 15.23
+	Hs
		245601 CUL4B_HUMAN (10-759): 0: 927: 82.31		TBL1X_HUMAN (396-661): 8.44e-63: 220: 19.79
+	Hs
		1043499 CUL4B_HUMAN (10-759): 0: 927: 82.31		FBXW7_HUMAN (314-594): 9.42e-60: 214: 14.53
+	Hs
		1043085 CUL4A_HUMAN (1-759): 0: 963: 100.00		WDR5B_HUMAN (179-512): 1.46e-45: 166: 14.29
+	Hs
		903208 CUL4A_HUMAN (1-759): 0: 963: 100.00		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		921556 CUL4A_HUMAN (1-759): 0: 963: 100.00		GBB2_HUMAN (462-661): 1.61e-37: 144: 12.20
+	Hs
		1043385 CUL4B_HUMAN (10-759): 0: 927: 82.31		SMU1_HUMAN (477-661): 1.05e-44: 169: 17.41
+	Hs
		1043441 CUL4B_HUMAN (10-759): 0: 927: 82.31		WDR5B_HUMAN (179-512): 1.46e-45: 166: 14.29
+	Hs
		903209 CUL4B_HUMAN (10-759): 0: 927: 82.31		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		1043114 CUL4A_HUMAN (1-759): 0: 963: 100.00		POC1B_HUMAN (70-392): 1.31e-14: 78.6: 12.96
+	Hs
		1043157 CUL4A_HUMAN (1-759): 0: 963: 100.00		SNR40_HUMAN (17-381): 1.88e-13: 74.4: 13.39
+	Hs
		1041647 CUL3_HUMAN (32-759): 0: 814: 38.23		TAF5_HUMAN (450-661): 8.05e-55: 202: 14.58
+	Hs
		1043469 CUL4B_HUMAN (10-759): 0: 927: 82.31		POC1B_HUMAN (70-392): 1.31e-14: 78.6: 12.96
+	Hs
		1043509 CUL4B_HUMAN (10-759): 0: 927: 82.31		SNR40_HUMAN (17-381): 1.88e-13: 74.4: 13.39
+	Hs
		1041692 CUL3_HUMAN (32-759): 0: 814: 38.23		SMU1_HUMAN (477-661): 1.05e-44: 169: 17.41
+	Hs
		903207 CUL3_HUMAN (32-759): 0: 814: 38.23		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		921555 CUL3_HUMAN (32-759): 0: 814: 38.23		GBB2_HUMAN (462-661): 1.61e-37: 144: 12.20
+	Hs
		1042101 CUL3_HUMAN (32-759): 0: 814: 38.23		POC1B_HUMAN (70-392): 1.31e-14: 78.6: 12.96