HitPredict

Interactor 1: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: SMU1 (Q2TAY7)
WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]
Gene: SMU1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	17041588
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 513
+	Hs
		1043589 CUL4B_HUMAN (1-913): 0: 1184: 100.00		WDR26_HUMAN (3-513): 2.59e-99: 314: 19.45
+	Hs
		903209 CUL4B_HUMAN (1-913): 0: 1184: 100.00		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		245601 CUL4B_HUMAN (1-913): 0: 1184: 100.00		TBL1X_HUMAN (252-512): 3.08e-62: 215: 18.38
+	Hs
		1043562 CUL4B_HUMAN (1-913): 0: 1184: 100.00		TBL1R_HUMAN (252-512): 4.37e-62: 213: 16.96
+	Hs
		1043509 CUL4B_HUMAN (1-913): 0: 1184: 100.00		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		1043441 CUL4B_HUMAN (1-913): 0: 1184: 100.00		WDR5B_HUMAN (428-512): 2.8e-18: 87.7: 22.35
+	Hs
		1043469 CUL4B_HUMAN (1-913): 0: 1184: 100.00		POC1B_HUMAN (429-513): 1.66e-17: 86.9: 22.35
+	Hs
		1043224 CUL4A_HUMAN (161-913): 0: 955: 81.83		WDR26_HUMAN (3-513): 2.59e-99: 314: 19.45
+	Hs
		929446 CUL4B_HUMAN (1-913): 0: 1184: 100.00		RACK1_HUMAN (277-377): 7.24e-11: 65.5: 33.33
+	Hs
		1016274 CUL4B_HUMAN (1-913): 0: 1184: 100.00		TBL3_HUMAN (213-376): 4.84e-09: 60.8: 24.55
+	Hs
		792982 CUL4A_HUMAN (161-913): 0: 955: 81.83		LIS1_HUMAN (4-472): 9.67e-90: 282: 15.13
+	Hs
		903208 CUL4A_HUMAN (161-913): 0: 955: 81.83		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		903207 CUL3_HUMAN (186-913): 0: 853: 37.19		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		1043234 CUL4A_HUMAN (161-913): 0: 955: 81.83		GBB4_HUMAN (323-511): 2.27e-26: 111: 21.47
+	Hs
		1043157 CUL4A_HUMAN (161-913): 0: 955: 81.83		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		921556 CUL4A_HUMAN (161-913): 0: 955: 81.83		GBB2_HUMAN (187-335): 1.43e-21: 97.7: 20.81
+	Hs
		560878 CUL4A_HUMAN (161-913): 0: 955: 81.83		GBB3_HUMAN (188-335): 3.06e-19: 90.8: 19.60
+	Hs
		1043085 CUL4A_HUMAN (161-913): 0: 955: 81.83		WDR5B_HUMAN (428-512): 2.8e-18: 87.7: 22.35
+	Hs
		1043114 CUL4A_HUMAN (161-913): 0: 955: 81.83		POC1B_HUMAN (429-513): 1.66e-17: 86.9: 22.35
+	Hs
		921555 CUL3_HUMAN (186-913): 0: 853: 37.19		GBB2_HUMAN (187-335): 1.43e-21: 97.7: 20.81