HitPredict

Interactor 1: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: Q6PK50 (Q6PK50)
Heat shock protein HSP 90-beta
Gene: HSP90AB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 351
+	Hs
		438154 CUL4B_HUMAN (1-913): 0: 1184: 100.00		HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00
+	Hs
		431833 CUL4B_HUMAN (1-913): 0: 1184: 100.00		HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92
+	Hs
		1043352 CUL4B_HUMAN (1-913): 0: 1184: 100.00		HS902_HUMAN (1-336): 4.86e-163: 460: 79.88
+	Hs
		538228 CUL4B_HUMAN (1-913): 0: 1184: 100.00		ENPL_HUMAN (2-351): 6.06e-139: 415: 42.54
+	Hs
		438153 CUL4A_HUMAN (161-913): 0: 955: 81.83		HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00
+	Hs
		431832 CUL4A_HUMAN (161-913): 0: 955: 81.83		HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92
+	Hs
		538227 CUL4A_HUMAN (161-913): 0: 955: 81.83		ENPL_HUMAN (2-351): 6.06e-139: 415: 42.54
+	Hs
		438152 CUL3_HUMAN (186-913): 0: 853: 37.19		HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00
+	Hs
		431831 CUL3_HUMAN (186-913): 0: 853: 37.19		HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92
+	Hs
		1041576 CUL3_HUMAN (186-913): 0: 853: 37.19		HS902_HUMAN (1-336): 4.86e-163: 460: 79.88
+	Hs
		438150 CUL1_HUMAN (213-913): 0: 778: 30.16		HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00
+	Hs
		431829 CUL1_HUMAN (213-913): 0: 778: 30.16		HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92
+	Hs
		538226 CUL3_HUMAN (186-913): 0: 853: 37.19		ENPL_HUMAN (2-351): 6.06e-139: 415: 42.54
+	Hs
		1041725 CUL3_HUMAN (186-913): 0: 853: 37.19		H90B3_HUMAN (1-345): 2.38e-137: 404: 79.13
+	Hs
		438151 CUL2_HUMAN (205-913): 0: 746: 27.53		HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00
+	Hs
		431830 CUL2_HUMAN (205-913): 0: 746: 27.53		HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92
+	Hs
		1040982 CUL1_HUMAN (213-913): 0: 778: 30.16		HS902_HUMAN (1-336): 4.86e-163: 460: 79.88
+	Hs
		1041320 CUL2_HUMAN (205-913): 0: 746: 27.53		HS902_HUMAN (1-336): 4.86e-163: 460: 79.88
+	Hs
		538224 CUL1_HUMAN (213-913): 0: 778: 30.16		ENPL_HUMAN (2-351): 6.06e-139: 415: 42.54
+	Hs
		538225 CUL2_HUMAN (205-913): 0: 746: 27.53		ENPL_HUMAN (2-351): 6.06e-139: 415: 42.54