HitPredict

Interactor 1: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: BRWD3 (Q6RI45)
Bromodomain and WD repeat-containing protein 3
Gene: BRWD3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.674

Property	Details
Experiments	31753913, 26496610, 31973889
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 1802
+	Hs
		1043064 CUL4A_HUMAN (161-913): 0: 955: 81.83		BRWD3_HUMAN (1-1802): 0: 1527: 100.00
+	Hs
		1016274 CUL4B_HUMAN (1-913): 0: 1184: 100.00		TBL3_HUMAN (1-437): 6.33e-71: 257: 13.48
+	Hs
		1043441 CUL4B_HUMAN (1-913): 0: 1184: 100.00		WDR5B_HUMAN (68-345): 2.77e-66: 230: 17.02
+	Hs
		1043469 CUL4B_HUMAN (1-913): 0: 1184: 100.00		POC1B_HUMAN (349-791): 2.25e-53: 197: 11.30
+	Hs
		1043611 CUL4B_HUMAN (1-913): 0: 1184: 100.00		BRWD1_HUMAN (1-295): 6.93e-44: 178: 15.29
+	Hs
		152876 CUL4B_HUMAN (1-913): 0: 1184: 100.00		APAF_HUMAN (402-753): 1.81e-43: 176: 11.75
+	Hs
		1043499 CUL4B_HUMAN (1-913): 0: 1184: 100.00		FBXW7_HUMAN (395-683): 2.37e-42: 169: 12.93
+	Hs
		903209 CUL4B_HUMAN (1-913): 0: 1184: 100.00		WDR5_HUMAN (453-689): 3.34e-36: 143: 12.30
+	Hs
		1043478 CUL4B_HUMAN (1-913): 0: 1184: 100.00		PHIP_HUMAN (1-171): 3.05e-22: 107: 7.98
+	Hs
		245601 CUL4B_HUMAN (1-913): 0: 1184: 100.00		TBL1X_HUMAN (420-556): 2.74e-22: 105: 15.89
+	Hs
		1043562 CUL4B_HUMAN (1-913): 0: 1184: 100.00		TBL1R_HUMAN (420-689): 1.51e-21: 102: 15.09
+	Hs
		1043509 CUL4B_HUMAN (1-913): 0: 1184: 100.00		SNR40_HUMAN (22-206): 1.57e-15: 82.2: 15.10
+	Hs
		1043637 CUL4B_HUMAN (1-913): 0: 1184: 100.00		FBW1B_HUMAN (183-495): 1.87e-12: 73.9: 24.46
+	Hs
		1043085 CUL4A_HUMAN (161-913): 0: 955: 81.83		WDR5B_HUMAN (68-345): 2.77e-66: 230: 17.02
+	Hs
		1043114 CUL4A_HUMAN (161-913): 0: 955: 81.83		POC1B_HUMAN (349-791): 2.25e-53: 197: 11.30
+	Hs
		1043252 CUL4A_HUMAN (161-913): 0: 955: 81.83		BRWD1_HUMAN (1-295): 6.93e-44: 178: 15.29
+	Hs
		792982 CUL4A_HUMAN (161-913): 0: 955: 81.83		LIS1_HUMAN (411-692): 6.51e-41: 158: 12.63
+	Hs
		903208 CUL4A_HUMAN (161-913): 0: 955: 81.83		WDR5_HUMAN (453-689): 3.34e-36: 143: 12.30
+	Hs
		1043124 CUL4A_HUMAN (161-913): 0: 955: 81.83		PHIP_HUMAN (1-171): 3.05e-22: 107: 7.98
+	Hs
		1043157 CUL4A_HUMAN (161-913): 0: 955: 81.83		SNR40_HUMAN (22-206): 1.57e-15: 82.2: 15.10