HitPredict

Interactor 1: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.664

Property	Details
Experiments	25189618, 30737378, 34026424
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 913 Hs			1 488
+	Hs
		1038357 CUL4B_HUMAN (1-913): 0: 1184: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		177290 CUL4B_HUMAN (1-913): 0: 1184: 100.00		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		1043137 CUL4A_HUMAN (161-913): 0: 955: 81.83		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1038356 CUL4A_HUMAN (161-913): 0: 955: 81.83		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1042193 CUL3_HUMAN (186-913): 0: 853: 37.19		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		177289 CUL4A_HUMAN (161-913): 0: 955: 81.83		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		1043628 CUL4B_HUMAN (1-913): 0: 1184: 100.00		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Mm
		140315 CUL3_MOUSE (186-913): 0: 852: 37.19		HDAC1_MOUSE (1-443): 0: 645: 90.29
+	Hs
		1038355 CUL3_HUMAN (186-913): 0: 853: 37.19		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1042740 CUL3_HUMAN (186-913): 0: 853: 37.19		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		1041243 CUL1_HUMAN (213-913): 0: 778: 30.16		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04