HitPredict

Interactor 1: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: TBL1R (Q9BZK7)
F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1)
Gene: TBL1XR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34026424
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 514
+	Hs
		245601 CUL4B_HUMAN (1-913): 0: 1184: 100.00		TBL1X_HUMAN (1-514): 1.2e-150: 444: 86.34
+	Hs
		1043499 CUL4B_HUMAN (1-913): 0: 1184: 100.00		FBXW7_HUMAN (39-423): 4.25e-69: 236: 15.64
+	Hs
		1043441 CUL4B_HUMAN (1-913): 0: 1184: 100.00		WDR5B_HUMAN (300-514): 6.92e-63: 210: 26.15
+	Hs
		1043469 CUL4B_HUMAN (1-913): 0: 1184: 100.00		POC1B_HUMAN (295-513): 2.29e-58: 202: 27.15
+	Hs
		1016274 CUL4B_HUMAN (1-913): 0: 1184: 100.00		TBL3_HUMAN (131-514): 2.98e-55: 200: 15.00
+	Hs
		903209 CUL4B_HUMAN (1-913): 0: 1184: 100.00		WDR5_HUMAN (17-334): 1.51e-56: 193: 14.46
+	Hs
		1043385 CUL4B_HUMAN (1-913): 0: 1184: 100.00		SMU1_HUMAN (329-513): 4.3e-39: 150: 19.00
+	Hs
		792982 CUL4A_HUMAN (161-913): 0: 955: 81.83		LIS1_HUMAN (4-430): 6.86e-96: 298: 17.26
+	Hs
		1043509 CUL4B_HUMAN (1-913): 0: 1184: 100.00		SNR40_HUMAN (50-195): 7.63e-12: 68.7: 11.92
+	Hs
		1043085 CUL4A_HUMAN (161-913): 0: 955: 81.83		WDR5B_HUMAN (300-514): 6.92e-63: 210: 26.15
+	Hs
		560878 CUL4A_HUMAN (161-913): 0: 955: 81.83		GBB3_HUMAN (197-510): 1.53e-60: 204: 19.20
+	Hs
		1043114 CUL4A_HUMAN (161-913): 0: 955: 81.83		POC1B_HUMAN (295-513): 2.29e-58: 202: 27.15
+	Hs
		903208 CUL4A_HUMAN (161-913): 0: 955: 81.83		WDR5_HUMAN (17-334): 1.51e-56: 193: 14.46
+	Hs
		1042101 CUL3_HUMAN (186-913): 0: 853: 37.19		POC1B_HUMAN (295-513): 2.29e-58: 202: 27.15
+	Hs
		903207 CUL3_HUMAN (186-913): 0: 853: 37.19		WDR5_HUMAN (17-334): 1.51e-56: 193: 14.46
+	Hs
		1043157 CUL4A_HUMAN (161-913): 0: 955: 81.83		SNR40_HUMAN (50-195): 7.63e-12: 68.7: 11.92
+	Hs
		1041692 CUL3_HUMAN (186-913): 0: 853: 37.19		SMU1_HUMAN (329-513): 4.3e-39: 150: 19.00
+	Hs
		1042655 CUL3_HUMAN (186-913): 0: 853: 37.19		NLE1_HUMAN (23-293): 5.57e-36: 141: 13.61
+	Hs
		903206 CUL1_HUMAN (213-913): 0: 778: 30.16		WDR5_HUMAN (17-334): 1.51e-56: 193: 14.46
+	Hs
		1041647 CUL3_HUMAN (186-913): 0: 853: 37.19		TAF5_HUMAN (164-376): 6.23e-14: 76.6: 23.72