HitPredict

Interactor 1: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: WDR12 (Q9GZL7)
Ribosome biogenesis protein WDR12 (WD repeat-containing protein 12)
Gene: WDR12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21145461
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 423
+	Hs
		245601 CUL4B_HUMAN (1-913): 0: 1184: 100.00		TBL1X_HUMAN (8-374): 1.42e-68: 229: 20.25
+	Hs
		903209 CUL4B_HUMAN (1-913): 0: 1184: 100.00		WDR5_HUMAN (222-421): 9.01e-50: 173: 25.62
+	Hs
		1043441 CUL4B_HUMAN (1-913): 0: 1184: 100.00		WDR5B_HUMAN (232-421): 1.8e-45: 161: 29.02
+	Hs
		1043469 CUL4B_HUMAN (1-913): 0: 1184: 100.00		POC1B_HUMAN (242-420): 2.17e-43: 159: 24.18
+	Hs
		1043499 CUL4B_HUMAN (1-913): 0: 1184: 100.00		FBXW7_HUMAN (224-421): 3e-37: 145: 20.00
+	Hs
		1043562 CUL4B_HUMAN (1-913): 0: 1184: 100.00		TBL1R_HUMAN (217-421): 7.46e-31: 125: 18.32
+	Hs
		1043509 CUL4B_HUMAN (1-913): 0: 1184: 100.00		SNR40_HUMAN (327-421): 1.19e-16: 82.5: 19.79
+	Hs
		1043637 CUL4B_HUMAN (1-913): 0: 1184: 100.00		FBW1B_HUMAN (111-409): 4.1e-10: 63.5: 24.76
+	Hs
		903208 CUL4A_HUMAN (161-913): 0: 955: 81.83		WDR5_HUMAN (222-421): 9.01e-50: 173: 25.62
+	Hs
		1043085 CUL4A_HUMAN (161-913): 0: 955: 81.83		WDR5B_HUMAN (232-421): 1.8e-45: 161: 29.02
+	Hs
		1043114 CUL4A_HUMAN (161-913): 0: 955: 81.83		POC1B_HUMAN (242-420): 2.17e-43: 159: 24.18
+	Hs
		792982 CUL4A_HUMAN (161-913): 0: 955: 81.83		LIS1_HUMAN (294-421): 2.01e-28: 117: 23.08
+	Hs
		1043319 CUL4A_HUMAN (161-913): 0: 955: 81.83		FBW1A_HUMAN (295-418): 9.43e-22: 99.6: 25.81
+	Hs
		1043157 CUL4A_HUMAN (161-913): 0: 955: 81.83		SNR40_HUMAN (327-421): 1.19e-16: 82.5: 19.79
+	Hs
		903207 CUL3_HUMAN (186-913): 0: 853: 37.19		WDR5_HUMAN (222-421): 9.01e-50: 173: 25.62
+	Hs
		1043297 CUL4A_HUMAN (161-913): 0: 955: 81.83		FBW1B_HUMAN (111-409): 4.1e-10: 63.5: 24.76
+	Hs
		197016 CUL3_HUMAN (186-913): 0: 853: 37.19		PRP4_HUMAN (187-419): 2.34e-43: 160: 15.92
+	Hs
		1042101 CUL3_HUMAN (186-913): 0: 853: 37.19		POC1B_HUMAN (242-420): 2.17e-43: 159: 24.18
+	Hs
		1042655 CUL3_HUMAN (186-913): 0: 853: 37.19		NLE1_HUMAN (289-420): 9.15e-33: 130: 25.90
+	Hs
		903206 CUL1_HUMAN (213-913): 0: 778: 30.16		WDR5_HUMAN (222-421): 9.01e-50: 173: 25.62