HitPredict

Interactor 1: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Interactor 2: RASF8 (Q8NHQ8)
Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1)
Gene: RASSF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.737

Property	Details
Experiments	24366813, 26186194, 26496610, 28514442, 32296183, 33961781
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1128 Hs			1 419
+	Hs
		277413 ASPP2_HUMAN (1-1128): 0: 599: 100.00		RASF9_HUMAN (2-411): 2.1e-120: 358: 21.45
+	Hs
		1043655 ASPP2_HUMAN (1-1128): 0: 599: 100.00		ASPP2_HUMAN (1-406): 1.62e-99: 322: 15.46
+	Hs
		63647 ASPP2_HUMAN (1-1128): 0: 599: 100.00		RASFA_HUMAN (2-410): 1.25e-99: 308: 14.66
+	Hs
		985563 Q05BL1_HUMAN (90-1128): 2.47e-152: 484: 99.90		RASF8_HUMAN (1-419): 8.08e-125: 369: 100.00
+	Hs
		972967 ASPP2_HUMAN (1-1128): 0: 599: 100.00		RASF7_HUMAN (1-405): 1.95e-77: 246: 33.42
+	Hs
		1245834 ASPP1_HUMAN (1-1128): 4.45e-135: 439: 45.38		RASF8_HUMAN (1-419): 8.08e-125: 369: 100.00
+	Hs
		277422 ASPP1_HUMAN (1-1128): 4.45e-135: 439: 45.38		RASF9_HUMAN (2-411): 2.1e-120: 358: 21.45
+	Hs
		63643 Q05BL1_HUMAN (90-1128): 2.47e-152: 484: 99.90		RASFA_HUMAN (2-410): 1.25e-99: 308: 14.66
+	Hs
		63664 ASPP1_HUMAN (1-1128): 4.45e-135: 439: 45.38		RASFA_HUMAN (2-410): 1.25e-99: 308: 14.66
+	Hs
		972977 ASPP1_HUMAN (1-1128): 4.45e-135: 439: 45.38		RASF7_HUMAN (1-405): 1.95e-77: 246: 33.42
+	Hs
		166977 ANR28_HUMAN (771-1049): 2.48e-23: 109: 13.78		RASF8_HUMAN (1-419): 8.08e-125: 369: 100.00
+	Dm
		1362200 Q9W2J2_DROME (126-1123): 2.51e-75: 272: 27.13		Q9VBP2_DROME (1-81): 8.78e-28: 117: 69.14