HitPredict

Interactor 1: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Interactor 2: B2CL2 (Q92843)
Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W)
Gene: BCL2L2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.799

Property	Details
Experiments	18719108, 18448430
Identification Methods	surface plasmon resonance, peptide array
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ank_2~Bcl-2
Common GO terms	GO:0005829 - cytosol GO:0042803 - protein homodimerization activity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1128 Hs			1 193
+	Hs
		489414 ASPP2_HUMAN (1-1128): 0: 599: 100.00		BCL2_HUMAN (9-193): 1.75e-61: 192: 35.32
+	Hs
		992073 ASPP2_HUMAN (1-1128): 0: 599: 100.00		B2CL1_HUMAN (6-185): 1.44e-56: 179: 38.96
+	Hs
		310048 TNKS1_HUMAN (808-1080): 1.68e-44: 178: 12.84		MCL1_HUMAN (19-180): 6.36e-46: 156: 21.82
+	Hs
		992198 TNKS2_HUMAN (893-1127): 6.78e-43: 172: 14.54		MCL1_HUMAN (19-180): 6.36e-46: 156: 21.82