HitPredict

Interactor 1: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Interactor 2: FRMD6 (Q96NE9)
FERM domain-containing protein 6 (Willin)
Gene: FRMD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1128 Hs			1 622
+	Hs
		1296379 ASPP1_HUMAN (1-1128): 4.45e-135: 439: 45.38		E41LA_HUMAN (18-452): 1.01e-75: 257: 16.96
+	Hs
		547096 KANK2_HUMAN (303-1049): 2.35e-63: 234: 16.00		EZRI_HUMAN (12-593): 3.93e-115: 357: 16.10
+	Hs
		518823 TPR_HUMAN (62-894): 9.75e-55: 211: 13.79		PTN4_HUMAN (4-536): 8.69e-120: 379: 14.29
+	Hs
		640252 KANK2_HUMAN (303-1049): 2.35e-63: 234: 16.00		PTN3_HUMAN (5-547): 9.8e-102: 331: 14.19
+	Hs
		518826 TPR_HUMAN (62-894): 9.75e-55: 211: 13.79		MERL_HUMAN (9-594): 1.95e-113: 353: 15.41
+	Hs
		640145 BARD1_HUMAN (676-1036): 1.54e-45: 179: 16.83		MOES_HUMAN (12-595): 1.26e-110: 345: 15.20
+	Hs
		1219853 ANKH1_HUMAN (922-1013): 2.42e-20: 100: 30.44		E41L5_HUMAN (5-598): 2.32e-127: 393: 14.73
+	Hs
		1144786 KANK2_HUMAN (303-1049): 2.35e-63: 234: 16.00		E41LA_HUMAN (18-452): 1.01e-75: 257: 16.96
+	Hs
		1330892 Q9H4D1_HUMAN (573-1024): 4.3e-26: 117: 11.58		E41L3_HUMAN (13-569): 1.1e-111: 361: 13.81
+	Hs
		883679 RIPK4_HUMAN (863-1024): 1.42e-25: 116: 19.63		E41L3_HUMAN (13-569): 1.1e-111: 361: 13.81
+	Hs
		299289 Q9H4D1_HUMAN (573-1024): 4.3e-26: 117: 11.58		FARP2_HUMAN (9-568): 9.2e-110: 355: 14.21
+	Hs
		299252 RIPK4_HUMAN (863-1024): 1.42e-25: 116: 19.63		FARP2_HUMAN (9-568): 9.2e-110: 355: 14.21
+	Hs
		719616 Q9H4D1_HUMAN (573-1024): 4.3e-26: 117: 11.58		MERL_HUMAN (9-594): 1.95e-113: 353: 15.41
+	Hs
		719429 RIPK4_HUMAN (863-1024): 1.42e-25: 116: 19.63		MERL_HUMAN (9-594): 1.95e-113: 353: 15.41
+	Hs
		166880 ANR28_HUMAN (771-1049): 2.48e-23: 109: 13.78		EZRI_HUMAN (12-593): 3.93e-115: 357: 16.10
+	Rn
		1014569 MYPT1_RAT (957-1059): 2.62e-16: 86.4: 36.89		MERL_RAT (9-579): 6.93e-111: 346: 15.48
+	Mm
		804962 MYPT1_MOUSE (891-1059): 3.49e-16: 86: 26.74		MERL_MOUSE (9-594): 1.94e-106: 335: 15.41
+	Hs
		640287 ANR50_HUMAN (836-995): 6.95e-17: 88.7: 16.88		PTN3_HUMAN (5-547): 9.8e-102: 331: 14.19
+	Hs
		1076940 ANR50_HUMAN (836-995): 6.95e-17: 88.7: 16.88		PTN14_HUMAN (20-336): 1.44e-73: 258: 19.75
+	Ce
		105085 G5ECD7_CAEEL (931-1059): 2.42e-13: 76.8: 29.41		H2KYX3_CAEEL (25-496): 1.23e-71: 246: 17.08