HitPredict

Interactor 1: DYR1A (Q13627)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)
Gene: DYRK1A

Interactor 2: RBM39 (Q14498)
RNA-binding protein 39 (CAPER alpha) (CAPERalpha) (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1)
Gene: RBM39

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30773093
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 763 Hs			1 530
+	Hs
		516508 DYR1A_HUMAN (1-763): 0: 613: 100.00		PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08
+	Hs
		1031320 DYR1A_HUMAN (1-763): 0: 613: 100.00		PABP4_HUMAN (41-422): 3.94e-60: 211: 17.22
+	Hs
		1043793 DYR1A_HUMAN (1-763): 0: 613: 100.00		ELAV3_HUMAN (434-530): 7.68e-17: 84.2: 12.87
+	Hs
		642764 DYR1A_HUMAN (1-763): 0: 613: 100.00		ELAV4_HUMAN (396-530): 1.79e-16: 83.1: 9.35
+	Hs
		1020254 DYR1A_HUMAN (1-763): 0: 613: 100.00		ELAV2_HUMAN (434-530): 7.45e-16: 81.1: 10.89
+	Hs
		162042 DYR1A_HUMAN (1-763): 0: 613: 100.00		HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93
+	Hs
		1044035 DYR1A_HUMAN (1-763): 0: 613: 100.00		MSI2H_HUMAN (149-309): 3.89e-15: 78.6: 28.57
+	Hs
		625633 CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85		PUF60_HUMAN (141-513): 7.12e-66: 225: 19.41
+	Hs
		516362 CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85		PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08
+	Sc
		376610 YAK1_YEAST (19-586): 3.53e-116: 371: 29.05		PABP_YEAST (40-441): 6.66e-53: 190: 12.17
+	Zm
		43418 B6TES5_MAIZE (136-502): 5.9e-117: 359: 25.40		A0A1D6PK18_MAIZE (396-516): 2.32e-36: 144: 42.15
+	Hs
		161966 MARK3_HUMAN (105-758): 1.17e-123: 389: 17.72		HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93
+	Zm
		11850 A0A1D6FHK3_MAIZE (103-525): 7.64e-118: 362: 22.50		A0A1D6II08_MAIZE (149-323): 7.45e-17: 85.5: 30.90
+	Zm
		9779 A0A1D6FHK3_MAIZE (103-525): 7.64e-118: 362: 22.50		A0A1D6EZQ5_MAIZE (149-323): 8.87e-17: 85.1: 30.90
+	Hs
		415020 CDK1_HUMAN (156-482): 1.29e-121: 368: 26.57		MSI2H_HUMAN (149-309): 3.89e-15: 78.6: 28.57
+	Hs
		625400 CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85		ELAV2_HUMAN (434-530): 7.45e-16: 81.1: 10.89