HitPredict

Interactor 1: DYR1A (Q13627)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)
Gene: DYRK1A

Interactor 2: KIF14 (Q15058)
Kinesin-like protein KIF14
Gene: KIF14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30979931, 31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FHA~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0015631 - tubulin binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 763 Hs			1 1648
+	Hs
		414925 CDK1_HUMAN (156-482): 1.29e-121: 368: 26.57		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		1015751 DYR1A_HUMAN (1-763): 0: 613: 100.00		KIF1A_HUMAN (354-1159): 1.48e-140: 477: 34.14
+	Hs
		116826 DYR1A_HUMAN (1-763): 0: 613: 100.00		KIF2A_HUMAN (163-845): 1.24e-108: 364: 20.90
+	Hs
		81875 DYR1A_HUMAN (1-763): 0: 613: 100.00		KIF28_HUMAN (362-726): 6.45e-67: 248: 42.04
+	Hs
		1268611 DYRK2_HUMAN (46-549): 5.03e-120: 375: 33.53		KIF3A_HUMAN (348-815): 1.16e-149: 477: 33.61
+	Hs
		166379 DYRK2_HUMAN (46-549): 5.03e-120: 375: 33.53		KIF3B_HUMAN (355-1075): 3.17e-145: 466: 27.37
+	Hs
		116775 MARK3_HUMAN (105-758): 1.17e-123: 389: 17.72		KIF2A_HUMAN (163-845): 1.24e-108: 364: 20.90
+	Hs
		253258 DYR1A_HUMAN (1-763): 0: 613: 100.00		KI21B_HUMAN (1182-1614): 1.63e-12: 75: 8.72
+	Hs
		1043915 DYR1A_HUMAN (1-763): 0: 613: 100.00		KI21A_HUMAN (1014-1619): 2.07e-11: 71.5: 6.91
+	Zm
		16406 A0A1D6N7V3_MAIZE (129-479): 1.99e-46: 179: 32.68		A0A1D6GMT7_MAIZE (325-1189): 2.37e-144: 475: 23.69
+	Hs
		155184 DYRK2_HUMAN (46-549): 5.03e-120: 375: 33.53		KIF3C_HUMAN (359-728): 8.78e-59: 220: 37.59