HitPredict

Interactor 1: DYR1A (Q13627)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)
Gene: DYRK1A

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	30979931
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 763 Hs			1 1025
+	Hs
		1043984 DYR1A_HUMAN (1-763): 0: 613: 100.00		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		1044147 DYR1A_HUMAN (1-763): 0: 613: 100.00		TARA_HUMAN (231-985): 1.44e-51: 201: 35.57
+	Hs
		1044121 DYR1A_HUMAN (1-763): 0: 613: 100.00		SCAPE_HUMAN (71-937): 4.97e-45: 179: 13.95
+	Hs
		1044162 DYR1A_HUMAN (1-763): 0: 613: 100.00		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		148781 DYR1A_HUMAN (1-763): 0: 613: 100.00		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		725159 DYR1A_HUMAN (1-763): 0: 613: 100.00		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18
+	Hs
		528372 DYR1A_HUMAN (1-763): 0: 613: 100.00		MYH6_HUMAN (559-1024): 5.56e-13: 75.9: 9.79
+	Hs
		728476 DYR1A_HUMAN (1-763): 0: 613: 100.00		MYH11_HUMAN (124-786): 1.25e-12: 74.7: 11.57
+	Hs
		255320 DYR1A_HUMAN (1-763): 0: 613: 100.00		HIP1R_HUMAN (626-929): 1.25e-09: 64.5: 19.56
+	Hs
		647929 MARK3_HUMAN (105-758): 1.17e-123: 389: 17.72		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		1268591 DYRK2_HUMAN (46-549): 5.03e-120: 375: 33.53		TARA_HUMAN (231-985): 1.44e-51: 201: 35.57
+	Hs
		415005 CDK1_HUMAN (156-482): 1.29e-121: 368: 26.57		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		415051 CDK1_HUMAN (156-482): 1.29e-121: 368: 26.57		SCAPE_HUMAN (71-937): 4.97e-45: 179: 13.95
+	Hs
		148173 DYRK3_HUMAN (7-531): 1.12e-117: 368: 30.64		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		148286 CDK1_HUMAN (156-482): 1.29e-121: 368: 26.57		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		681696 AKT1_HUMAN (38-466): 4.44e-117: 363: 19.42		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		960128 CDK3_HUMAN (156-436): 1.81e-117: 358: 26.12		MYH2_HUMAN (122-873): 5.69e-17: 89: 9.31
+	Hs
		522604 CDK3_HUMAN (156-436): 1.81e-117: 358: 26.12		MYH7_HUMAN (101-931): 7.33e-17: 88.6: 10.36
+	Hs
		522542 CDK3_HUMAN (156-436): 1.81e-117: 358: 26.12		MYH1_HUMAN (122-873): 2.75e-15: 83.2: 8.13
+	Hs
		528368 CDK3_HUMAN (156-436): 1.81e-117: 358: 26.12		MYH6_HUMAN (559-1024): 5.56e-13: 75.9: 9.79