HitPredict

Interactor 1: DYR1A (Q13627)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)
Gene: DYRK1A

Interactor 2: RAB6B (Q9NRW1)
Ras-related protein Rab-6B (EC 3.6.5.2)
Gene: RAB6B

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	36950384
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 763 Hs			1 208
+	Hs
		844511 DYR1A_HUMAN (1-763): 0: 613: 100.00		RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98
+	Hs
		918863 DYR1A_HUMAN (1-763): 0: 613: 100.00		RAB1A_HUMAN (1-207): 7.26e-89: 261: 34.30
+	Hs
		592658 DYR1A_HUMAN (1-763): 0: 613: 100.00		RAB6A_HUMAN (1-208): 1.37e-84: 250: 90.87
+	Hs
		895349 DYR1A_HUMAN (1-763): 0: 613: 100.00		RAB5B_HUMAN (13-178): 5.66e-49: 160: 45.78
+	Hs
		895069 DYR1A_HUMAN (1-763): 0: 613: 100.00		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89
+	Hs
		592109 MARK3_HUMAN (105-758): 1.17e-123: 389: 17.72		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Hs
		647864 MARK3_HUMAN (105-758): 1.17e-123: 389: 17.72		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		625247 CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85		RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98
+	Hs
		625461 CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85		RB11B_HUMAN (7-208): 5.29e-82: 244: 28.91
+	Hs
		647857 MARK3_HUMAN (105-758): 1.17e-123: 389: 17.72		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89