HitPredict

Interactor 1: DYR1A (Q13627)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)
Gene: DYRK1A

Interactor 2: G3BP2 (Q9UN86)
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)
Gene: G3BP2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	36950384
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005737 - cytoplasm GO:1990904 - ribonucleoprotein complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 763 Hs			1 482
+	Hs
		1043815 DYR1A_HUMAN (1-763): 0: 613: 100.00		SAFB1_HUMAN (141-482): 2.07e-42: 163: 16.43
+	Hs
		1043783 DYR1A_HUMAN (1-763): 0: 613: 100.00		SAFB2_HUMAN (141-482): 1.89e-41: 160: 14.69
+	Hs
		647983 MARK3_HUMAN (105-758): 1.17e-123: 389: 17.72		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		1268606 DYRK2_HUMAN (46-549): 5.03e-120: 375: 33.53		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		1044050 DYR1A_HUMAN (1-763): 0: 613: 100.00		CELF6_HUMAN (287-416): 2.28e-15: 80.3: 16.54
+	Hs
		625639 CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		647884 MARK3_HUMAN (105-758): 1.17e-123: 389: 17.72		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		414901 CDK1_HUMAN (156-482): 1.29e-121: 368: 26.57		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	At
		1105732 KSG7_ARATH (127-524): 6.36e-119: 364: 25.78		Q9FND0_ARATH (1-454): 1.1e-54: 191: 23.59
+	Hs
		414930 CDK1_HUMAN (156-482): 1.29e-121: 368: 26.57		SAFB1_HUMAN (141-482): 2.07e-42: 163: 16.43
+	Hs
		414914 CDK1_HUMAN (156-482): 1.29e-121: 368: 26.57		SAFB2_HUMAN (141-482): 1.89e-41: 160: 14.69