Interactor 1: FCL (Q13630)
GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (Protein FX) (Red cell NADP(H)-binding protein) (Short-chain dehydrogenase/reductase family 4E member 1)
Gene: GFUS
Interactor 2: FCL (Q13630)
GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (Protein FX) (Red cell NADP(H)-binding protein) (Short-chain dehydrogenase/reductase family 4E member 1)
Gene: GFUS
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.72 | 1.00 | 0.849 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, unassigned1304, 23774504 |
| Identification Methods | two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach, x-ray crystallography |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Epimerase~Epimerase |
| Common GO terms | GO:0005829 - cytosol GO:0007159 - leukocyte cell-cell adhesion GO:0009055 - electron transfer activity GO:0010595 - positive regulation of endothelial cell migration GO:0019673 - GDP-mannose metabolic process and 6 others more... |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
