HitPredict

Interactor 1: PTC1 (Q13635)
Protein patched homolog 1 (PTC) (PTC1)
Gene: PTCH1

Interactor 2: SIA10 (Q9Y274)
Type 2 lactosamine alpha-2,3-sialyltransferase (EC 2.4.99.-) (CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI) (ST3Gal VI) (ST3GalVI) (Sialyltransferase 10)
Gene: ST3GAL6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1447 Hs			1 331
+	Hs
		1014784 PTC1_HUMAN (1-1447): 0: 1579: 100.00		SIA4C_HUMAN (38-329): 7.53e-95: 286: 39.60
+	Hs
		1044404 PTC1_HUMAN (1-1447): 0: 1579: 100.00		SIA8D_HUMAN (88-326): 4.6e-64: 208: 23.02
+	Hs
		1044439 PTC1_HUMAN (1-1447): 0: 1579: 100.00		SIA7D_HUMAN (63-325): 6.24e-63: 203: 20.00
+	Hs
		1044391 PTC1_HUMAN (1-1447): 0: 1579: 100.00		SIA7C_HUMAN (84-325): 1.28e-47: 164: 21.46