HitPredict

Interactor 1: FHL1 (Q13642)
Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM-protein 1) (SLIM) (SLIM-1)
Gene: FHL1

Interactor 2: TITIN (Q8WZ42)
Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)
Gene: TTN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.613

Property	Details
Experiments	22778266, 23414517
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 34350
+	Hs
		816266 LIMS1_HUMAN (98-240): 6.01e-25: 104: 24.67		TITIN_HUMAN (1-34350): 0: 28064: 100.00
+	Hs
		1151801 ABLM2_HUMAN (97-239): 3.89e-22: 98.9: 21.29		TITIN_HUMAN (1-34350): 0: 28064: 100.00
+	Hs
		150606 ABLM1_HUMAN (126-268): 7.44e-18: 86.2: 22.07		TITIN_HUMAN (1-34350): 0: 28064: 100.00
+	Hs
		1050732 FHL2_HUMAN (3-92): 4.15e-15: 76.2: 34.78		TITIN_HUMAN (1-34350): 0: 28064: 100.00
+	Hs
		362937 PAXI_HUMAN (37-245): 1.04e-68: 226: 28.44		FINC_HUMAN (26307-28070): 3.11e-129: 464: 16.42
+	Hs
		962502 FHL1_HUMAN (1-323): 7.74e-90: 272: 100.00		MYPC1_HUMAN (15875-16031): 5.27e-09: 68.2: 26.67
+	Ce
		136803 Q3S1I9_CAEEL (57-229): 1.15e-41: 147: 30.29		UNC89_CAEEL (29573-29860): 5.4e-21: 108: 20.68
+	Hs
		1044609 FHL3_HUMAN (3-92): 3.86e-17: 81.9: 33.70		OBSCN_HUMAN (30666-30849): 2.08e-16: 92.7: 24.32
+	Ce
		107557 G5EFG1_CAEEL (98-228): 1.38e-10: 64.3: 27.82		UNC89_CAEEL (29573-29860): 5.4e-21: 108: 20.68
+	Hs
		962503 FHL3_HUMAN (3-92): 3.86e-17: 81.9: 33.70		MYPC1_HUMAN (15875-16031): 5.27e-09: 68.2: 26.67
+	Hs
		962504 FHL2_HUMAN (3-92): 4.15e-15: 76.2: 34.78		MYPC1_HUMAN (15875-16031): 5.27e-09: 68.2: 26.67