HitPredict

Interactor 1: FHL3 (Q13643)
Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM-protein 2) (SLIM-2)
Gene: FHL3

Interactor 2: WNK1 (Q9H4A3)
Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Erythrocyte 65 kDa protein) (p65) (Kinase deficient protein) (Protein kinase lysine-deficient 1) (Protein kinase with no lysine 1) (hWNK1)
Gene: WNK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.658

Property	Details
Experiments	32296183, 25416956, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 280 Hs			1 2382
+	Hs
		1050785 FHL2_HUMAN (4-156): 1.41e-24: 101: 26.45		WNK1_HUMAN (1-2382): 0: 877: 100.00
+	Hs
		1025195 PDLI5_HUMAN (3-155): 6.13e-48: 169: 28.76		AAPK1_HUMAN (195-737): 1.29e-123: 404: 16.40
+	Mm
		949382 ABLM1_MOUSE (151-277): 7.34e-26: 108: 22.66		TNIK_MOUSE (198-1222): 1.32e-131: 451: 13.65
+	Hs
		681836 FHL1_HUMAN (66-279): 2.38e-43: 151: 29.17		AKT1_HUMAN (159-548): 6.99e-124: 402: 18.55
+	Hs
		1050766 FHL2_HUMAN (4-156): 1.41e-24: 101: 26.45		WNK3_HUMAN (1397-2378): 2.71e-57: 222: 18.10
+	Hs
		1044558 FHL1_HUMAN (66-279): 2.38e-43: 151: 29.17		NEK7_HUMAN (221-467): 5.66e-24: 106: 29.30