HitPredict

Interactor 1: FHL3 (Q13643)
Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM-protein 2) (SLIM-2)
Gene: FHL3

Interactor 2: PKHA5 (Q9HAU0)
Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)
Gene: PLEKHA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 280 Hs			1 1116
+	Hs
		1050797 FHL2_HUMAN (4-156): 1.41e-24: 101: 26.45		PKHA5_HUMAN (1-1116): 0: 609: 100.00
+	Hs
		150593 ABLM1_HUMAN (3-147): 6.59e-28: 114: 24.03		PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32
+	Ce
		136803 Q3S1I9_CAEEL (3-219): 4.02e-45: 155: 27.15		UNC89_CAEEL (727-1109): 1.99e-56: 217: 12.25
+	Mm
		1143674 TGFI1_MOUSE (3-218): 1.72e-67: 218: 26.85		ITCH_MOUSE (6-234): 3.37e-28: 124: 16.16
+	Hs
		200183 TGFI1_HUMAN (3-218): 5.41e-68: 219: 27.32		ITCH_HUMAN (9-234): 1.29e-27: 123: 15.93
+	Hs
		1293396 PDLI5_HUMAN (3-155): 6.13e-48: 169: 28.76		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		816279 LIMS1_HUMAN (37-278): 1.46e-46: 160: 23.48		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		1044576 FHL1_HUMAN (66-279): 2.38e-43: 151: 29.17		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Ce
		107557 G5EFG1_CAEEL (3-150): 2.87e-13: 71.6: 26.00		UNC89_CAEEL (727-1109): 1.99e-56: 217: 12.25
+	Hs
		1167433 PDLI7_HUMAN (158-278): 1.55e-32: 126: 24.79		MPRIP_HUMAN (95-395): 8.25e-38: 155: 13.86
+	Hs
		1331378 PDLI7_HUMAN (158-278): 1.55e-32: 126: 24.79		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		1050786 FHL2_HUMAN (4-156): 1.41e-24: 101: 26.45		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		125735 PDLI7_HUMAN (158-278): 1.55e-32: 126: 24.79		WWP2_HUMAN (10-213): 2.29e-27: 122: 19.51
+	Hs
		1327916 PDLI7_HUMAN (158-278): 1.55e-32: 126: 24.79		WWP1_HUMAN (3-240): 7.83e-24: 110: 14.94
+	Hs
		816266 LIMS1_HUMAN (37-278): 1.46e-46: 160: 23.48		TITIN_HUMAN (275-1090): 3.45e-10: 67: 9.15
+	Hs
		1044559 FHL1_HUMAN (66-279): 2.38e-43: 151: 29.17		TITIN_HUMAN (275-1090): 3.45e-10: 67: 9.15
+	Hs
		150606 ABLM1_HUMAN (3-147): 6.59e-28: 114: 24.03		TITIN_HUMAN (275-1090): 3.45e-10: 67: 9.15
+	Hs
		1151801 ABLM2_HUMAN (3-148): 1.19e-24: 104: 22.93		TITIN_HUMAN (275-1090): 3.45e-10: 67: 9.15
+	Hs
		1050732 FHL2_HUMAN (4-156): 1.41e-24: 101: 26.45		TITIN_HUMAN (275-1090): 3.45e-10: 67: 9.15