HitPredict

Interactor 1: RIN1 (Q13671)
Ras and Rab interactor 1 (Ras inhibitor JC99) (Ras interaction/interference protein 1)
Gene: RIN1

Interactor 2: GRB7 (Q14451)
Growth factor receptor-bound protein 7 (B47) (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein)
Gene: GRB7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34718347
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~RA, RA~RA
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 783 Hs			1 532
+	Hs
		855796 GAPD1_HUMAN (132-596): 4.11e-109: 365: 13.10		VAV2_HUMAN (81-526): 4.93e-78: 264: 14.77
+	Hs
		411796 RIN3_HUMAN (9-369): 5.23e-38: 154: 23.21		LCK_HUMAN (317-527): 2.74e-57: 200: 20.00
+	Hs
		523025 TENS3_HUMAN (28-227): 4.82e-43: 171: 20.37		SRC_HUMAN (351-528): 1.08e-46: 172: 24.32
+	Hs
		581028 RIN3_HUMAN (9-369): 5.23e-38: 154: 23.21		PLCG1_HUMAN (200-532): 6.64e-50: 187: 14.69
+	Hs
		1117726 RIN3_HUMAN (9-369): 5.23e-38: 154: 23.21		Q4LE43_HUMAN (200-532): 3.88e-49: 184: 14.69
+	Hs
		412275 RIN3_HUMAN (9-369): 5.23e-38: 154: 23.21		FYN_HUMAN (357-529): 5.57e-50: 182: 20.88
+	Hs
		523075 RIN3_HUMAN (9-369): 5.23e-38: 154: 23.21		SRC_HUMAN (351-528): 1.08e-46: 172: 24.32
+	Hs
		181764 SOCS1_HUMAN (49-192): 1.35e-26: 110: 24.32		LCK_HUMAN (317-527): 2.74e-57: 200: 20.00
+	Hs
		181765 SOCS1_HUMAN (49-192): 1.35e-26: 110: 24.32		FYN_HUMAN (357-529): 5.57e-50: 182: 20.88
+	Hs
		782797 TENS3_HUMAN (28-227): 4.82e-43: 171: 20.37		CSK_HUMAN (394-525): 1.94e-28: 119: 28.78
+	Hs
		181770 SOCS1_HUMAN (49-192): 1.35e-26: 110: 24.32		YES_HUMAN (366-528): 8.94e-48: 175: 19.53
+	Dm
		337705 Q9VRS2_DROME (46-176): 6.45e-31: 129: 31.06		SRC64_DROME (353-529): 7.92e-38: 148: 20.22
+	Hs
		782795 TENS2_HUMAN (4-230): 1.01e-38: 157: 18.60		CSK_HUMAN (394-525): 1.94e-28: 119: 28.78
+	Hs
		66465 RIN3_HUMAN (9-369): 5.23e-38: 154: 23.21		A8K3B6_HUMAN (394-525): 1.47e-28: 120: 29.50
+	Dm
		337683 EGRAP_DROME (13-173): 7.82e-30: 125: 26.35		SRC64_DROME (353-529): 7.92e-38: 148: 20.22
+	Hs
		782808 RIN3_HUMAN (9-369): 5.23e-38: 154: 23.21		CSK_HUMAN (394-525): 1.94e-28: 119: 28.78
+	Hs
		782828 TENS1_HUMAN (10-225): 3.96e-37: 152: 16.46		CSK_HUMAN (394-525): 1.94e-28: 119: 28.78
+	Hs
		924632 TENS2_HUMAN (4-230): 1.01e-38: 157: 18.60		GRB2_HUMAN (427-513): 2.66e-13: 71: 29.89
+	Hs
		69536 RIN3_HUMAN (9-369): 5.23e-38: 154: 23.21		B0LPF3_HUMAN (427-513): 2.66e-13: 71: 29.89
+	Hs
		924717 RIN3_HUMAN (9-369): 5.23e-38: 154: 23.21		GRB2_HUMAN (427-513): 2.66e-13: 71: 29.89