HitPredict

Interactor 1: ITA7 (Q13683)
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]
Gene: ITGA7

Interactor 2: FHL2 (Q14192)
Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3)
Gene: FHL2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.637

Property	Details
Experiments	15117962, 10906324
Identification Methods	two hybrid, affinity chromatography technology, coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1181 Hs			1 279
+	Hs
		1044588 ITA7_HUMAN (1-1181): 0: 1423: 100.00		FHL3_HUMAN (66-279): 2.11e-40: 143: 27.32
+	Hs
		639888 ITA3_HUMAN (1-1137): 0: 922: 33.62		FHL2_HUMAN (1-279): 4.64e-77: 237: 100.00
+	Hs
		200158 ITA4_HUMAN (1-1146): 0: 821: 22.84		TGFI1_HUMAN (3-218): 4.81e-69: 222: 26.39
+	Mm
		1307899 ITA2B_MOUSE (4-1115): 0: 789: 24.89		LPXN_MOUSE (3-219): 6.21e-60: 196: 28.57
+	Hs
		419175 ITAV_HUMAN (31-1111): 0: 859: 26.66		PAXI_HUMAN (187-279): 1.89e-18: 86.9: 23.53
+	Hs
		238945 ITA4_HUMAN (1-1146): 0: 821: 22.84		LPXN_HUMAN (3-98): 4.14e-21: 93.4: 23.96
+	Hs
		530504 ITA4_HUMAN (1-1146): 0: 821: 22.84		PAXI_HUMAN (187-279): 1.89e-18: 86.9: 23.53
+	Mm
		1208581 ITA2B_MOUSE (4-1115): 0: 789: 24.89		PDLI5_MOUSE (3-159): 3.76e-17: 82.8: 26.75
+	Hs
		566880 ITA2_HUMAN (27-506): 4.59e-40: 163: 16.92		FHL2_HUMAN (1-279): 4.64e-77: 237: 100.00
+	Ce
		107579 PAT2_CAEEL (935-1147): 3.06e-20: 99.6: 21.82		G5EFG1_CAEEL (3-150): 1.53e-19: 90.1: 30.67