HitPredict

Interactor 1: AAMP (Q13685)
Angio-associated migratory cell protein
Gene: AAMP

Interactor 2: WNK1 (Q9H4A3)
Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Erythrocyte 65 kDa protein) (p65) (Kinase deficient protein) (Protein kinase lysine-deficient 1) (Protein kinase with no lysine 1) (hWNK1)
Gene: WNK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 434 Hs			1 2382
+	Mm
		949357 TBL1R_MOUSE (300-433): 1.23e-23: 104: 16.78		TNIK_MOUSE (198-1222): 1.32e-131: 451: 13.65
+	Hs
		793038 LIS1_HUMAN (2-164): 2.78e-24: 105: 15.34		TNIK_HUMAN (198-1222): 4.7e-123: 427: 13.42
+	Sc
		419809 NLE1_YEAST (348-433): 7.98e-21: 96.7: 20.69		SNF1_YEAST (221-671): 1.23e-123: 407: 21.96
+	Hs
		254137 WDR1_HUMAN (100-421): 6.13e-14: 75.9: 24.15		AKT3_HUMAN (163-539): 2.39e-123: 400: 18.65
+	Hs
		1025190 FBXW7_HUMAN (90-253): 7.25e-10: 63.2: 28.92		AAPK1_HUMAN (195-737): 1.29e-123: 404: 16.40
+	Hs
		681967 FBXW7_HUMAN (90-253): 7.25e-10: 63.2: 28.92		AKT1_HUMAN (159-548): 6.99e-124: 402: 18.55
+	Hs
		1240443 POC1A_HUMAN (2-119): 3.42e-17: 84.7: 11.86		NEK7_HUMAN (221-467): 5.66e-24: 106: 29.30