HitPredict

Interactor 1: ARFRP (Q13795)
ADP-ribosylation factor-related protein 1 (ARF-related protein 1) (ARP)
Gene: ARFRP1

Interactor 2: CYH1 (Q15438)
Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog B2-1)
Gene: CYTH1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	1.00	0.680

Property	Details
Experiments	10092663
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Arf~PH, Arf~Sec7
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 201 Hs			1 398
+	Mm
		913234 ARF6_MOUSE (5-186): 1.1e-86: 254: 29.67		CYH1_MOUSE (1-398): 0: 515: 98.24
+	Hs
		912917 ARF6_HUMAN (5-186): 1.1e-86: 254: 29.67		CYH1_HUMAN (1-398): 0: 514: 100.00
+	Hs
		913064 ARF6_HUMAN (5-186): 1.1e-86: 254: 29.67		CYH2_HUMAN (3-398): 3.26e-177: 501: 83.08
+	Rn
		913236 ARF6_RAT (5-186): 1.1e-86: 254: 29.67		CYH2_RAT (3-398): 1.04e-176: 499: 82.58
+	Hs
		950545 ARF1_HUMAN (1-191): 2.98e-72: 218: 30.37		CYH2_HUMAN (3-398): 3.26e-177: 501: 83.08
+	Hs
		913002 ARF6_HUMAN (5-186): 1.1e-86: 254: 29.67		PSD4_HUMAN (3-390): 1.22e-103: 331: 23.76
+	Hs
		912959 ARF6_HUMAN (5-186): 1.1e-86: 254: 29.67		IQEC1_HUMAN (51-397): 3.98e-103: 328: 27.20
+	Dm
		778393 ARF6_DROME (5-186): 6.1e-85: 250: 29.67		Q6U9V3_DROME (56-367): 1.91e-100: 325: 30.21
+	Hs
		913219 ARF6_HUMAN (5-186): 1.1e-86: 254: 29.67		BIG1_HUMAN (5-268): 2.33e-94: 311: 40.07
+	Hs
		913147 ARF6_HUMAN (5-186): 1.1e-86: 254: 29.67		PSD3_HUMAN (92-390): 1.34e-84: 280: 24.08
+	Hs
		914499 RB11A_HUMAN (1-201): 1.2e-64: 200: 16.10		BIG1_HUMAN (5-268): 2.33e-94: 311: 40.07
+	Dm
		897468 ARF1_DROME (1-189): 5.81e-72: 217: 30.16		Q9VJW1_DROME (39-285): 4.98e-87: 290: 41.04
+	Hs
		914254 RB11A_HUMAN (1-201): 1.2e-64: 200: 16.10		GBF1_HUMAN (5-377): 1.37e-90: 300: 25.88
+	Hs
		914498 RB11A_HUMAN (1-201): 1.2e-64: 200: 16.10		BIG2_HUMAN (5-268): 2.02e-88: 294: 39.11
+	Hs
		950731 ARF5_HUMAN (1-190): 2.65e-69: 210: 30.00		PSD3_HUMAN (92-390): 1.34e-84: 280: 24.08
+	Dm
		53572 ARF1_DROME (1-189): 5.81e-72: 217: 30.16		A1Z8W9_DROME (27-258): 2.03e-80: 271: 32.23
+	Sc
		502942 ARF1_YEAST (1-189): 2.32e-69: 211: 32.80		SEC7_YEAST (39-250): 3.99e-81: 273: 41.59
+	Hs
		914406 RB11A_HUMAN (1-201): 1.2e-64: 200: 16.10		PSD3_HUMAN (92-390): 1.34e-84: 280: 24.08
+	Dm
		53567 O18332_DROME (3-199): 1.91e-66: 204: 21.83		A1Z8W9_DROME (27-258): 2.03e-80: 271: 32.23
+	Sc
		350838 YPT1_YEAST (5-197): 2.5e-65: 201: 19.69		SEC7_YEAST (39-250): 3.99e-81: 273: 41.59