HitPredict

Interactor 1: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Interactor 2: DZIP3 (Q86Y13)
E3 ubiquitin-protein ligase DZIP3 (EC 2.3.2.27) (DAZ-interacting protein 3) (RING-type E3 ubiquitin transferase DZIP3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138)
Gene: DZIP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2472 Hs			1 1208
+	Hs
		865042 SPTN1_HUMAN (1-2472): 0: 714: 100.00		TTC3_HUMAN (703-1207): 1.23e-42: 173: 19.15
+	Hs
		148786 SPTN1_HUMAN (1-2472): 0: 714: 100.00		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Hs
		522612 SPTN1_HUMAN (1-2472): 0: 714: 100.00		MYH7_HUMAN (507-1075): 1.4e-18: 94.3: 8.25
+	Hs
		1045492 SPTN1_HUMAN (1-2472): 0: 714: 100.00		CK5P2_HUMAN (522-912): 1.36e-10: 68.1: 10.02
+	Hs
		148142 SPTN2_HUMAN (141-1932): 1.25e-65: 250: 20.41		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Hs
		865031 SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52		TTC3_HUMAN (703-1207): 1.23e-42: 173: 19.15
+	Hs
		963324 SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52		DCTN1_HUMAN (639-961): 5.05e-41: 167: 15.84
+	Hs
		865033 DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59		TTC3_HUMAN (703-1207): 1.23e-42: 173: 19.15
+	Hs
		974072 DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59		DCTN1_HUMAN (639-961): 5.05e-41: 167: 15.84
+	Hs
		164657 SPTN2_HUMAN (141-1932): 1.25e-65: 250: 20.41		CK5P2_HUMAN (522-912): 1.36e-10: 68.1: 10.02
+	Hs
		166683 CE290_HUMAN (808-2443): 1.12e-32: 142: 10.61		TTC3_HUMAN (703-1207): 1.23e-42: 173: 19.15
+	Hs
		166706 CE290_HUMAN (808-2443): 1.12e-32: 142: 10.61		DCTN1_HUMAN (639-961): 5.05e-41: 167: 15.84
+	Hs
		148690 SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Hs
		1059231 GOGB1_HUMAN (2-1186): 3.65e-38: 160: 10.57		RNF43_HUMAN (1104-1206): 7.85e-24: 110: 26.79
+	Hs
		166748 CE290_HUMAN (808-2443): 1.12e-32: 142: 10.61		RN149_HUMAN (1134-1206): 1.2e-21: 101: 32.90
+	Hs
		963399 SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52		CK5P2_HUMAN (522-912): 1.36e-10: 68.1: 10.02
+	Hs
		148841 PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Mm
		1322158 PLEC_MOUSE (1-1250): 7.03e-38: 159: 10.80		SYVN1_MOUSE (1108-1192): 9.12e-15: 80.9: 32.58
+	Hs
		166769 CE290_HUMAN (808-2443): 1.12e-32: 142: 10.61		CK5P2_HUMAN (522-912): 1.36e-10: 68.1: 10.02
+	Hs
		149277 SPTN4_HUMAN (961-2371): 1.09e-21: 105: 13.80		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53