HitPredict

Interactor 1: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Interactor 2: FACD2 (Q9BXW9)
Fanconi anemia group D2 protein (Protein FACD2)
Gene: FANCD2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26297932, 31180492
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2472 Hs			1 1451
+	Mm
		82768 B9EKJ1_MOUSE (1-2472): 0: 706: 98.18		FACD2_MOUSE (1-1439): 0: 1973: 74.76
+	Hs
		360662 SPTA1_HUMAN (1-2472): 2.98e-159: 552: 54.81		FACD2_HUMAN (1-1441): 0: 2030: 100.00
+	Hs
		963408 SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52		FACD2_HUMAN (1-1441): 0: 2030: 100.00
+	Hs
		1068651 PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18		FACD2_HUMAN (1-1441): 0: 2030: 100.00
+	Mm
		1194235 PLEC_MOUSE (1-1250): 7.03e-38: 159: 10.80		FACD2_MOUSE (1-1439): 0: 1973: 74.76
+	Mm
		1143714 SPTB2_MOUSE (1408-2420): 1.22e-29: 132: 18.86		FACD2_MOUSE (1-1439): 0: 1973: 74.76
+	Hs
		211655 ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15		FACD2_HUMAN (1-1441): 0: 2030: 100.00
+	Mm
		1186631 ACTN1_MOUSE (1862-2210): 1.97e-10: 68.6: 21.99		FACD2_MOUSE (1-1439): 0: 1973: 74.76
+	Mm
		885083 ACTN4_MOUSE (1843-2219): 1.04e-09: 66.2: 20.05		FACD2_MOUSE (1-1439): 0: 1973: 74.76