Interactor 1: DX39B (Q13838)
Spliceosome RNA helicase DDX39B (EC 3.6.4.13) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (DEAD box protein UAP56) (HLA-B-associated transcript 1 protein)
Gene: DDX39B

Interactor 2: THOC2 (Q8NI27)
THO complex subunit 2 (Tho2) (hTREX120)
Gene: THOC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 26496610, 15998806, 17190602, 23222130, 32989256, 35271311, 37071682, 11979277
Identification Methods affinity chromatography technology, cross-linking study, biochemical, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Helicase_C~Thoc2, Helicase_C~THOC2_N
Common GO terms GO:0000346 - transcription export complex
GO:0003729 - mRNA binding
GO:0005654 - nucleoplasm
GO:0006406 - mRNA export from nucleus
GO:0008380 - RNA splicing
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 428
Hs

1 1593
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Last updated: 15 Jul 2024