HitPredict

Interactor 1: DX39B (Q13838)
Spliceosome RNA helicase DDX39B (EC 3.6.4.13) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (DEAD box protein UAP56) (HLA-B-associated transcript 1 protein)
Gene: DDX39B

Interactor 2: API5 (Q9BZZ5)
Apoptosis inhibitor 5 (API-5) (Antiapoptosis clone 11 protein) (AAC-11) (Cell migration-inducing gene 8 protein) (Fibroblast growth factor 2-interacting factor) (FIF) (Protein XAGL)
Gene: API5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	30021884, 35271311, 37071682
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0005737 - cytoplasm and 1 others more... GO:0016607 - nuclear speck
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 524
+	Hs
		117211 DX39A_HUMAN (1-428): 3.89e-128: 378: 89.95		API5_HUMAN (1-524): 0: 773: 100.00
+	Hs
		134199 DDX3X_HUMAN (3-423): 4.76e-124: 375: 27.84		API5_HUMAN (1-524): 0: 773: 100.00
+	Dm
		1099521 DX39B_DROME (1-425): 1.1e-136: 400: 84.27		API5_DROME (1-500): 0: 659: 45.96
+	Hs
		757752 IF4A3_HUMAN (52-415): 7.9e-81: 256: 38.36		API5_HUMAN (1-524): 0: 773: 100.00