Interactor 1: EXOS2 (Q13868)
Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4)
Gene: EXOSC2
Interactor 2: EXOS7 (Q15024)
Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8)
Gene: EXOSC7
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.973 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26496610, 27173435, 24981860, 33961781, 12419256, 15231747, 26186194, 28514442, 11719186 |
| Identification Methods | affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ECR1_N~RNase_PH, ECR1_N~RNase_PH_C |
| Common GO terms | GO:0000175 - 3'-5'-RNA exonuclease activity GO:0000176 - nuclear exosome (RNase complex) GO:0000177 - cytoplasmic exosome (RNase complex) GO:0000178 - exosome (RNase complex) GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and 12 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Sp | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | Sp | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Pf | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | Sp | |
|
|||||||||||
| + | Sp | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Tb | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Tb | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
