Interactor 1: EXOS2 (Q13868)
Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4)
Gene: EXOSC2

Interactor 2: EXOS6 (Q5RKV6)
Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog) (hMtr3) (p11)
Gene: EXOSC6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.892

The method score is based on:

Property Details
Experiments 24981860, 26496610, 33961781, 11719186
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ECR1_N~RNase_PH
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0003723 - RNA binding
GO:0005634 - nucleus
and 9 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 293
Hs

1 272
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ At
+ Sp
+ At
+ Sp
+ Dm
+ Sc
+ Sp
+ At
+ Dm
+ At
+ Sp
+ Sc
+ Sc
+ Tb

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024