HitPredict

Interactor 1: PTK6 (Q13882)
Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)
Gene: PTK6

Interactor 2: KHDR2 (Q5VWX1)
KH domain-containing, RNA-binding, signal transduction-associated protein 2 (Sam68-like mammalian protein 1) (SLM-1) (hSLM-1)
Gene: KHDRBS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	25416956, 31515488
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 451 Hs			1 349
+	Mm
		763412 FYN_MOUSE (10-450): 0: 521: 42.35		KHDR2_MOUSE (1-349): 2.58e-149: 426: 95.42
+	Hs
		433822 LYN_HUMAN (3-449): 5.02e-177: 506: 38.19		KHDR2_HUMAN (1-349): 6.2e-151: 430: 100.00
+	Mm
		763394 FYN_MOUSE (10-450): 0: 521: 42.35		KHDR1_MOUSE (3-349): 9.08e-129: 377: 62.32
+	Mm
		403437 SRC_MOUSE (3-450): 0: 517: 43.08		KHDR1_MOUSE (3-349): 9.08e-129: 377: 62.32
+	Mm
		980964 YES_MOUSE (10-450): 1.7e-179: 514: 42.63		KHDR1_MOUSE (3-349): 9.08e-129: 377: 62.32
+	Mm
		639447 LYN_MOUSE (3-449): 3.28e-176: 504: 38.41		KHDR1_MOUSE (3-349): 9.08e-129: 377: 62.32
+	Hs
		789110 FRK_HUMAN (1-447): 0: 526: 41.09		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Hs
		412149 FYN_HUMAN (10-450): 0: 521: 42.35		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Hs
		522933 SRC_HUMAN (3-450): 0: 521: 43.30		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Hs
		433330 YES_HUMAN (10-450): 0: 519: 42.86		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Hs
		411689 LCK_HUMAN (3-449): 0: 517: 39.07		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Hs
		442815 HCK_HUMAN (4-449): 8.95e-179: 511: 39.82		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Hs
		454827 FGR_HUMAN (10-450): 3.32e-177: 508: 42.41		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Hs
		433719 LYN_HUMAN (3-449): 5.02e-177: 506: 38.19		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Hs
		991758 PTK6_HUMAN (1-451): 2.09e-175: 500: 100.00		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Hs
		782780 CSK_HUMAN (4-448): 3.18e-160: 461: 35.82		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Hs
		991737 ITK_HUMAN (7-447): 1.9e-152: 448: 32.82		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Dm
		337713 SRC64_DROME (10-449): 1.52e-164: 476: 42.04		Q9W255_DROME (4-302): 3.79e-88: 272: 37.12
+	Hs
		337484 ABL1_HUMAN (1-449): 2.48e-170: 509: 35.17		SF01_HUMAN (8-209): 6.71e-57: 196: 27.01
+	Hs
		789069 ABL2_HUMAN (2-449): 1.97e-164: 495: 35.02		SF01_HUMAN (8-209): 6.71e-57: 196: 27.01