HitPredict

Interactor 1: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C

Interactor 2: SRSF7 (Q16629)
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Gene: SRSF7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2221 Hs			1 238
+	Hs
		432702 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		951960 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		1031322 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00
+	Hs
		992766 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		516510 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		1031434 SCN2A_HUMAN (1221-1548): 8.66e-16: 86.5: 16.45		PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00
+	Hs
		516654 SCN2A_HUMAN (1221-1548): 8.66e-16: 86.5: 16.45		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		132307 CAC1A_HUMAN (1535-1966): 2.05e-14: 81.9: 8.28		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		1303351 SCN2A_HUMAN (1221-1548): 8.66e-16: 86.5: 16.45		PABP3_HUMAN (6-192): 4.81e-18: 84.4: 14.74
+	Dm
		597098 SCN60_DROME (938-1075): 7.5e-12: 73.6: 27.54		PABP_DROME (12-95): 2.2e-17: 82.5: 26.97