HitPredict

Interactor 1: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Interactor 2: CHD8 (Q9HCK8)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.12) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
Gene: CHD8

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	36950384
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 355 Hs			1 2581
+	Hs
		852179 ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02		CHD8_HUMAN (1-2581): 0: 2318: 100.00
+	Hs
		516702 PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93		CHD8_HUMAN (1-2581): 0: 2318: 100.00
+	Hs
		610059 ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40		CHD8_HUMAN (1-2581): 0: 2318: 100.00
+	Hs
		1018471 HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		162028 HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1018661 ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		852032 ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1048064 HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		1018458 PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		516483 PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		609829 ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		162050 HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		1059824 ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		852058 ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		1031332 PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		516522 PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		453315 ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		609866 ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		453364 ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		609764 ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40		SMCA4_HUMAN (69-1478): 0: 806: 23.14