HitPredict

Interactor 1: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	23530064, 25900982, 36199071
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0042752 - regulation of circadian rhythm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 355 Hs			1 605
+	Hs
		162186 HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1306046 ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		852208 ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1031501 PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		516754 PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1048270 HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		162182 HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1306041 ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		852199 ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1031492 PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		516733 PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1048172 HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		852125 ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		903216 HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		162000 HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		903463 ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		852006 ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		903196 PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		516438 PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		609790 ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33