HitPredict

Interactor 1: LRP8 (Q14114)
Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2)
Gene: LRP8

Interactor 2: SNX17 (Q15036)
Sorting nexin-17
Gene: SNX17

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	24705369, 12169628
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 963 Hs			1 470
+	Hs
		957521 VLDLR_HUMAN (5-286): 1.44e-33: 141: 23.49		SNX17_HUMAN (1-470): 0: 713: 100.00
+	Hs
		957606 LRP2_HUMAN (195-464): 3.85e-10: 66.4: 16.03		SNX17_HUMAN (1-470): 0: 713: 100.00
+	Hs
		351069 LDLR_HUMAN (683-895): 4.15e-09: 62.6: 10.65		SNX17_HUMAN (1-470): 0: 713: 100.00
+	Hs
		992667 LRP1_HUMAN (5-257): 6.13e-09: 62.6: 13.53		SNX17_HUMAN (1-470): 0: 713: 100.00