HitPredict

Interactor 1: DAG1 (Q14118)
Dystroglycan 1 (Dystroglycan) (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)]
Gene: DAG1

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19531213
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 895 Hs			1 665
+	Oc
		101982 DAG1_RABIT (1-895): 9.3e-162: 497: 93.74		G1SR27_RABIT (2-158): 6.97e-33: 128: 19.91
+	Hs
		557685 DAG1_HUMAN (1-895): 7.39e-154: 476: 100.00		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		924561 DAG1_HUMAN (1-895): 7.39e-154: 476: 100.00		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		203241 SYNJ1_HUMAN (180-822): 3.46e-23: 108: 13.52		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Hs
		1056926 MDC1_HUMAN (98-885): 3e-18: 92.7: 11.71		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Hs
		554292 MUC1_HUMAN (67-890): 1.18e-26: 119: 9.42		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		203208 SYNJ1_HUMAN (180-822): 3.46e-23: 108: 13.52		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		203218 SYNJ1_HUMAN (180-822): 3.46e-23: 108: 13.52		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		203228 SYNJ1_HUMAN (180-822): 3.46e-23: 108: 13.52		ITSN1_HUMAN (68-454): 2.48e-21: 101: 14.01
+	Hs
		924760 PRG4_HUMAN (350-894): 1.68e-13: 76.9: 13.21		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		203191 SYNJ1_HUMAN (180-822): 3.46e-23: 108: 13.52		VINEX_HUMAN (67-445): 2.37e-15: 81.7: 19.82
+	Hs
		203192 SYNJ1_HUMAN (180-822): 3.46e-23: 108: 13.52		SRBS2_HUMAN (3-155): 4.65e-11: 68.2: 30.86
+	Hs
		203230 SYNJ1_HUMAN (180-822): 3.46e-23: 108: 13.52		SH319_HUMAN (164-469): 4.12e-09: 61.9: 13.31
+	Rn
		192744 SYNJ1_RAT (180-750): 2.69e-17: 89.6: 12.27		SRBS2_RAT (3-155): 3.11e-11: 68.9: 30.25