HitPredict

Interactor 1: DSG2 (Q14126)
Desmoglein-2 (Cadherin family member 5) (HDGC)
Gene: DSG2

Interactor 2: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1118 Hs			1 236
+	Hs
		1048610 DSG2_HUMAN (1-1118): 0: 1174: 100.00		RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48
+	Hs
		950987 DSG2_HUMAN (1-1118): 0: 1174: 100.00		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		925270 DSG2_HUMAN (1-1118): 0: 1174: 100.00		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		892364 DSG2_HUMAN (1-1118): 0: 1174: 100.00		RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00
+	Hs
		564523 DSG2_HUMAN (1-1118): 0: 1174: 100.00		RHOQ_HUMAN (23-236): 1.99e-73: 223: 50.00
+	Hs
		545367 DSG2_HUMAN (1-1118): 0: 1174: 100.00		RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43
+	Hs
		900461 DSG2_HUMAN (1-1118): 0: 1174: 100.00		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		893994 DSG2_HUMAN (1-1118): 0: 1174: 100.00		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		1048664 DSG2_HUMAN (1-1118): 0: 1174: 100.00		RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27
+	Hs
		925399 DSG4_HUMAN (3-1052): 0: 912: 35.14		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		521847 CADH1_HUMAN (22-670): 0: 577: 31.67		RAB1A_HUMAN (21-234): 6.38e-76: 229: 20.55
+	Cl
		94527 CADH1_CANLF (30-670): 0: 572: 30.64		RAB1A_CANLF (21-234): 6.38e-76: 229: 20.55
+	Hs
		521840 CADH1_HUMAN (22-670): 0: 577: 31.67		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		521837 CADH1_HUMAN (22-670): 0: 577: 31.67		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		580224 CADH2_HUMAN (1-489): 2.19e-63: 234: 18.52		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		580220 CADH2_HUMAN (1-489): 2.19e-63: 234: 18.52		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		580218 CADH2_HUMAN (1-489): 2.19e-63: 234: 18.52		RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00
+	Hs
		545200 CADH2_HUMAN (1-489): 2.19e-63: 234: 18.52		RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43
+	Hs
		606304 CADH3_HUMAN (29-596): 2.57e-61: 227: 32.87		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		580261 CADH2_HUMAN (1-489): 2.19e-63: 234: 18.52		RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27