HitPredict

Interactor 1: TRI29 (Q14134)
Tripartite motif-containing protein 29 (Ataxia telangiectasia group D-associated protein)
Gene: TRIM29

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	25416956, 16189514
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:1900181 - negative regulation of protein localization to nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 588 Hs			1 669
+	Hs
		1048738 TRI29_HUMAN (1-588): 0: 603: 100.00		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		537021 TRI27_HUMAN (140-503): 7.63e-79: 259: 14.42		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		1310203 TRIM1_HUMAN (91-432): 5.04e-65: 228: 17.42		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Mm
		1322218 TRIM3_MOUSE (136-566): 1.1e-76: 259: 15.75		TSC1_MOUSE (48-630): 3.36e-32: 135: 13.67
+	Hs
		1078906 TRIM5_HUMAN (140-533): 1.09e-83: 271: 17.10		ITSN1_HUMAN (75-640): 4.07e-22: 104: 13.88
+	Hs
		1219901 TRI42_HUMAN (151-383): 7.89e-43: 165: 19.57		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		1356051 TRIM1_HUMAN (91-432): 5.04e-65: 228: 17.42		LZTS1_HUMAN (26-653): 2.54e-34: 140: 35.06
+	Hs
		584960 RO52_HUMAN (140-588): 2.7e-92: 293: 16.74		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		584968 RO52_HUMAN (140-588): 2.7e-92: 293: 16.74		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		584985 RO52_HUMAN (140-588): 2.7e-92: 293: 16.74		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		1078905 TRIM8_HUMAN (171-531): 3.4e-66: 227: 18.43		ITSN1_HUMAN (75-640): 4.07e-22: 104: 13.88
+	Hs
		1343227 TRI36_HUMAN (150-392): 5.6e-50: 186: 19.76		MTCL1_HUMAN (56-644): 5.72e-34: 141: 14.24
+	Hs
		528393 TRIM6_HUMAN (140-485): 2.68e-80: 262: 18.77		MYH6_HUMAN (140-554): 2.32e-09: 63.1: 9.14
+	Hs
		522639 TRIM6_HUMAN (140-485): 2.68e-80: 262: 18.77		MYH7_HUMAN (140-540): 9.01e-09: 61.2: 9.45
+	Hs
		536877 TRI27_HUMAN (140-503): 7.63e-79: 259: 14.42		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		149258 TRIM4_HUMAN (143-462): 3.46e-75: 249: 11.73		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		1052780 TRI25_HUMAN (104-416): 2.68e-62: 218: 24.68		MYO5C_HUMAN (318-668): 7.57e-17: 87.4: 12.02
+	Hs
		1357714 TRI35_HUMAN (136-483): 1.7e-71: 239: 13.44		MRCKB_HUMAN (197-560): 2.09e-10: 66.2: 13.44
+	Hs
		1051477 TRI36_HUMAN (150-392): 5.6e-50: 186: 19.76		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		1145945 TRI36_HUMAN (150-392): 5.6e-50: 186: 19.76		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52