Interactor 1: DELE1 (Q14154)
DAP3-binding cell death enhancer 1 (DAP3-binding cell death enhancer 1, long form) (DELE1(L)) (Death ligand signal enhancer) [Cleaved into: DAP3-binding cell death enhancer 1 short form (DELE1(S)) (S-DELE1)]
Gene: DELE1

Interactor 2: E2AK1 (Q9BQI3)
Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled repressor) (HCR) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (hHRI) (Hemin-sensitive initiation factor 2-alpha kinase)
Gene: EIF2AK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.657

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0140468 - HRI-mediated signaling
GO:1990641 - response to iron ion starvation
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 515
Hs

1 630
+ Hs
+ Hs
+ Hs
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Last updated: 15 Jul 2024