HitPredict

Interactor 1: G5EC72 (G5EC72)
PDZ and LIM domain protein Zasp
Gene: alp-1

Interactor 2: SRC1 (G5EE56)
Tyrosine protein-kinase src-1 (EC 2.7.10.2) (SRC oncogene related protein 1)
Gene: src-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 425 Ce			1 533
+	Ce
		104985 G5EC72_CAEEL (1-425): 9.83e-122: 361: 100.00		SRC2_CAEEL (1-532): 0: 524: 43.15
+	Ce
		104986 G5EC72_CAEEL (1-425): 9.83e-122: 361: 100.00		ABL1_CAEEL (11-525): 4.92e-152: 467: 36.13
+	Hs
		523001 TRIP6_HUMAN (31-271): 5.17e-30: 123: 16.48		SRC_HUMAN (1-530): 0: 544: 48.45
+	Ce
		106629 G5EFG1_CAEEL (96-288): 1.23e-12: 71.5: 15.82		SRC1_CAEEL (1-533): 0: 579: 100.00
+	Hs
		442837 TRIP6_HUMAN (31-271): 5.17e-30: 123: 16.48		HCK_HUMAN (1-529): 0: 525: 44.34
+	Hs
		254384 LDB3_HUMAN (88-273): 1.5e-18: 89.9: 14.09		SRC_HUMAN (1-530): 0: 544: 48.45
+	Hs
		111447 PDLI7_HUMAN (50-284): 1e-14: 77.7: 13.12		J3QRU1_HUMAN (1-530): 0: 546: 48.28
+	Hs
		433484 PDLI7_HUMAN (50-284): 1e-14: 77.7: 13.12		YES_HUMAN (1-530): 0: 546: 48.28
+	Hs
		411822 AJUBA_HUMAN (71-271): 1.45e-20: 95.7: 14.63		LCK_HUMAN (1-530): 3.31e-180: 518: 43.88
+	Hs
		412085 PAXI_HUMAN (215-271): 1.62e-10: 65: 28.07		FYN_HUMAN (1-530): 0: 547: 49.26
+	Hs
		433288 PAXI_HUMAN (215-271): 1.62e-10: 65: 28.07		YES_HUMAN (1-530): 0: 546: 48.28
+	Hs
		522857 PAXI_HUMAN (215-271): 1.62e-10: 65: 28.07		SRC_HUMAN (1-530): 0: 544: 48.45
+	Ce
		107567 G5EFG1_CAEEL (96-288): 1.23e-12: 71.5: 15.82		SRC2_CAEEL (1-532): 0: 524: 43.15
+	Hs
		442793 PAXI_HUMAN (215-271): 1.62e-10: 65: 28.07		HCK_HUMAN (1-529): 0: 525: 44.34
+	Hs
		411641 PAXI_HUMAN (215-271): 1.62e-10: 65: 28.07		LCK_HUMAN (1-530): 3.31e-180: 518: 43.88
+	Hs
		433646 PAXI_HUMAN (215-271): 1.62e-10: 65: 28.07		LYN_HUMAN (1-529): 1.41e-178: 514: 43.02
+	Hs
		337395 PAXI_HUMAN (215-271): 1.62e-10: 65: 28.07		ABL1_HUMAN (42-525): 3.28e-165: 499: 39.43
+	Ce
		107570 G5EFG1_CAEEL (96-288): 1.23e-12: 71.5: 15.82		ABL1_CAEEL (11-525): 4.92e-152: 467: 36.13
+	Ce
		106914 G5EEL1_CAEEL (218-288): 6.46e-12: 69.2: 21.13		ABL1_CAEEL (11-525): 4.92e-152: 467: 36.13
+	Hs
		238957 LPXN_HUMAN (215-273): 1.58e-11: 67.3: 27.12		BTK_HUMAN (1-525): 8.72e-157: 463: 32.32