HitPredict

Interactor 1: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Interactor 2: LRC27 (Q9C0I9)
Leucine-rich repeat-containing protein 27
Gene: LRRC27

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_1~LRR_8, LRR_8~LRR_8
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1630 Hs			1 530
+	Hs
		1049984 SCRIB_HUMAN (1-1630): 0: 978: 100.00		LRSM1_HUMAN (42-191): 3.51e-36: 144: 31.79
+	Hs
		232877 SCRIB_HUMAN (1-1630): 0: 978: 100.00		PHLP1_HUMAN (2-263): 5.96e-23: 105: 17.88
+	Hs
		1050046 SCRIB_HUMAN (1-1630): 0: 978: 100.00		LRRC1_HUMAN (67-345): 4.8e-20: 95.2: 14.95
+	Hs
		1050047 SCRIB_HUMAN (1-1630): 0: 978: 100.00		LGR4_HUMAN (43-182): 5.76e-17: 86.3: 20.42
+	Hs
		1050066 SCRIB_HUMAN (1-1630): 0: 978: 100.00		LRC40_HUMAN (80-316): 3.69e-09: 61.3: 14.18
+	At
		1324073 FLS2_ARATH (8-621): 1.42e-111: 385: 21.36		IRK_ARATH (115-433): 1.51e-33: 137: 11.01
+	At
		249728 FLS2_ARATH (8-621): 1.42e-111: 385: 21.36		BAME3_ARATH (40-239): 2.81e-21: 100: 15.71
+	At
		1324076 FLS2_ARATH (8-621): 1.42e-111: 385: 21.36		MIK1_ARATH (1-194): 5.09e-20: 96.3: 16.58
+	At
		99021 FLS2_ARATH (8-621): 1.42e-111: 385: 21.36		RGI4_ARATH (1-173): 1.21e-18: 91.7: 17.42
+	At
		1338953 Y1571_ARATH (1-644): 5.09e-114: 391: 18.62		BRL2_ARATH (53-419): 6.09e-13: 73.6: 11.87
+	At
		1167629 FLS2_ARATH (8-621): 1.42e-111: 385: 21.36		ERL2_ARATH (1-149): 3.27e-11: 68.1: 14.69
+	At
		1114705 FLS2_ARATH (8-621): 1.42e-111: 385: 21.36		ERECT_ARATH (276-417): 3.95e-10: 64.7: 8.16
+	At
		221778 FLS2_ARATH (8-621): 1.42e-111: 385: 21.36		BAME1_ARATH (255-414): 6.2e-09: 60.8: 8.43
+	At
		249735 RGI1_ARATH (50-829): 2.79e-97: 343: 17.75		BAME3_ARATH (40-239): 2.81e-21: 100: 15.71
+	At
		99012 ERL2_ARATH (1-454): 8.53e-99: 343: 25.16		RGI4_ARATH (1-173): 1.21e-18: 91.7: 17.42
+	At
		1338063 RGI1_ARATH (50-829): 2.79e-97: 343: 17.75		PXC2_ARATH (199-427): 1.28e-15: 82: 7.27
+	Zm
		19443 A0A1D6HD42_MAIZE (13-467): 1.44e-102: 357: 24.65		A0A1D6HD42_MAIZE (294-415): 2.07e-09: 62.4: 10.32
+	At
		85103 ERL2_ARATH (1-454): 8.53e-99: 343: 25.16		RGI2_ARATH (2-148): 2.01e-13: 75.5: 16.67
+	At
		1338065 RGI1_ARATH (50-829): 2.79e-97: 343: 17.75		BRL2_ARATH (53-419): 6.09e-13: 73.6: 11.87
+	At
		221789 RGI1_ARATH (50-829): 2.79e-97: 343: 17.75		BAME1_ARATH (255-414): 6.2e-09: 60.8: 8.43