HitPredict

Interactor 1: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.641

Property	Details
Experiments	38280479, 30126976, 22078877
Identification Methods	proximity labelling technology, p8 filamentous phage display, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1630 Hs			1 400
+	Hs
		808600 SCRIB_HUMAN (1-1630): 0: 978: 100.00		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		1326803 MFHA1_HUMAN (79-386): 6.54e-31: 134: 35.37		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		280067 MPDZ_HUMAN (953-1212): 1.61e-30: 134: 21.40		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		1021560 DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		1301440 ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		280032 MPDZ_HUMAN (953-1212): 1.61e-30: 134: 21.40		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		808565 DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		808867 ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Mm
		1143518 DLG4_MOUSE (812-1187): 6.74e-49: 189: 22.42		MAGI3_MOUSE (3-246): 8.06e-44: 165: 18.88
+	Hs
		280050 MPDZ_HUMAN (953-1212): 1.61e-30: 134: 21.40		KIBRA_HUMAN (123-265): 3.08e-45: 169: 18.88
+	Mm
		1143429 DLG4_MOUSE (812-1187): 6.74e-49: 189: 22.42		NED4L_MOUSE (129-395): 4.63e-24: 106: 11.96
+	Hs
		1301441 ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Mm
		93273 DLG4_MOUSE (812-1187): 6.74e-49: 189: 22.42		E9PXB7_MOUSE (129-395): 7.76e-23: 102: 12.68
+	Hs
		1021531 DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68		KIBRA_HUMAN (123-265): 3.08e-45: 169: 18.88
+	Hs
		280084 MPDZ_HUMAN (953-1212): 1.61e-30: 134: 21.40		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09
+	Mm
		93267 DLG3_MOUSE (724-947): 3.57e-19: 96.3: 31.23		E9PXB7_MOUSE (129-395): 7.76e-23: 102: 12.68
+	Mm
		808344 DLG3_MOUSE (724-947): 3.57e-19: 96.3: 31.23		NEDD4_MOUSE (129-328): 8.42e-21: 96.6: 10.44
+	Hs
		1271021 DLG3_HUMAN (724-947): 1.74e-19: 97.4: 31.23		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20