Interactor 1: GIT2 (Q14161)
ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)
Gene: GIT2

Interactor 2: GIT2 (Q14161)
ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)
Gene: GIT2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 12473661
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Ank_2, Ank_2~ArfGap, Ank_2~GIT_SHD, ArfGap~ArfGap, ArfGap~GIT_SHD, GIT1_C~GIT1_C, GIT_CC~GIT_CC, GIT_SHD~GIT_SHD
Common GO terms GO:0005096 - GTPase activator activity
GO:0005654 - nucleoplasm
GO:0005925 - focal adhesion
GO:0007420 - brain development
GO:0008277 - regulation of G protein-coupled receptor signaling pathway
and 6 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 759
Hs

1 759
+ Hs
+ Gg
+ Hs
+ Rn
+ Mm
+ Mm
+ Mm
+ Dr
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm

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Last updated: 15 Jul 2024