Interactor 1: GIT2 (Q14161)
ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)
Gene: GIT2
Interactor 2: ARHG6 (Q15052)
Rho guanine nucleotide exchange factor 6 (Alpha-Pix) (COOL-2) (PAK-interacting exchange factor alpha) (Rac/Cdc42 guanine nucleotide exchange factor 6)
Gene: ARHGEF6
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 1.00 | 0.946 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 33961781, 32296183, 32203420, unassigned1304, unassigned2213 |
| Identification Methods | affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, validated two hybrid, two hybrid prey pooling approach, two hybrid array, mammalian protein protein interaction trap |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ArfGap~PH, GIT_SHD~RhoGEF67_u2 |
| Common GO terms | GO:0005096 - GTPase activator activity |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
