HitPredict

Interactor 1: GIT2 (Q14161)
ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)
Gene: GIT2

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ArfGap~PH
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 759 Hs			1 779
+	Hs
		1331684 GIT1_HUMAN (1-758): 7.22e-141: 434: 63.74		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1206049 MIB1_HUMAN (54-671): 1.06e-66: 240: 11.62		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		161455 MYPT1_HUMAN (94-670): 7.76e-54: 203: 10.75		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		60417 POTEF_HUMAN (79-665): 1.93e-53: 202: 12.79		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Mm
		1148423 GIT1_MOUSE (1-758): 1.06e-139: 431: 63.43		CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40
+	Mm
		1112606 AGAP2_MOUSE (3-224): 1.24e-64: 236: 32.00		CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40
+	Hs
		1153457 AGAP1_HUMAN (3-224): 1.19e-59: 218: 33.33		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		161388 MYPT1_HUMAN (94-670): 7.76e-54: 203: 10.75		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1022473 AGAP1_HUMAN (3-224): 1.19e-59: 218: 33.33		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		1206058 MIB1_HUMAN (54-671): 1.06e-66: 240: 11.62		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		1167408 AGAP2_HUMAN (3-224): 2.94e-54: 204: 32.00		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		161391 MYPT1_HUMAN (94-670): 7.76e-54: 203: 10.75		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		161387 MYPT1_HUMAN (94-670): 7.76e-54: 203: 10.75		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81
+	Hs
		1334860 AGAP1_HUMAN (3-224): 1.19e-59: 218: 33.33		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		1205980 MIB1_HUMAN (54-671): 1.06e-66: 240: 11.62		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		1190998 AGAP3_HUMAN (3-224): 5.35e-57: 211: 35.11		RHG22_HUMAN (29-181): 1.62e-33: 139: 26.95
+	Hs
		1231307 AGAP3_HUMAN (3-224): 5.35e-57: 211: 35.11		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		161400 MYPT1_HUMAN (94-670): 7.76e-54: 203: 10.75		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		1231287 ARAP2_HUMAN (7-186): 2.94e-51: 196: 32.24		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		161453 MYPT1_HUMAN (94-670): 7.76e-54: 203: 10.75		TARA_HUMAN (49-471): 7.83e-20: 97.3: 15.21