Interactor 1: IKKE (Q14164)
Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)
Gene: IKBKE

Interactor 2: SLK (Q9H2G2)
STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)
Gene: SLK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17353931
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase, Pkinase~TBK1_CCD1, Pkinase~TBK1_ULD
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 716
Hs

1 1235
+ Rn
+ Hs
+ Gm
+ At
+ At
+ Rn
+ At
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Bt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024