HitPredict

Interactor 1: DOCK1 (Q14185)
Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180)
Gene: DOCK1

Interactor 2: DOCK1 (Q14185)
Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180)
Gene: DOCK1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 37071682, 15723800
Identification Methods cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DHR-2_Lobe_A~DHR-2_Lobe_A, DHR-2_Lobe_A~DHR-2_Lobe_B, DHR-2_Lobe_B~DHR-2_Lobe_C, DHR-2_Lobe_C~DHR-2_Lobe_C, DOCK-C2~DOCK-C2, DOCK-C2~DOCK_N, SH3_1~SH3_1
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 14 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1865
Hs

1 1865
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024