HitPredict

Interactor 1: TFDP1 (Q14186)
Transcription factor Dp-1 (DRTF1-polypeptide 1) (DRTF1) (E2F dimerization partner 1)
Gene: TFDP1

Interactor 2: PCGF6 (Q9BYE7)
Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134)
Gene: PCGF6

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.722

Property	Details
Experiments	27705803, 24981860, 28514442, 33961781, 22325352
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 410 Hs			1 350
+	Hs
		1050567 TFDP2_HUMAN (2-392): 0: 567: 60.47		PCGF6_HUMAN (1-350): 1.95e-96: 291: 100.00
+	Hs
		1050532 TFDP1_HUMAN (1-394): 0: 690: 100.00		RING2_HUMAN (85-303): 3.51e-32: 124: 14.49
+	Hs
		987969 TFDP1_HUMAN (1-394): 0: 690: 100.00		RING1_HUMAN (109-211): 1.44e-25: 108: 25.96
+	Mm
		996146 TFDP1_MOUSE (1-394): 0: 668: 95.43		RING2_MOUSE (85-303): 2.38e-32: 125: 14.49
+	Hs
		1050566 TFDP2_HUMAN (2-392): 0: 567: 60.47		RING2_HUMAN (85-303): 3.51e-32: 124: 14.49