HitPredict

Interactor 1: SIM2 (Q14190)
Single-minded homolog 2 (Class E basic helix-loop-helix protein 15) (bHLHe15)
Gene: SIM2

Interactor 2: TEBP (Q15185)
Prostaglandin E synthase 3 (EC 5.3.99.3) (Cytosolic prostaglandin E2 synthase) (cPGES) (Hsp90 co-chaperone) (Progesterone receptor complex p23) (Telomerase-binding protein p23)
Gene: PTGES3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	35914814, 25036637
Identification Methods	two hybrid, two hybrid fragment pooling approach, luminescence based mammalian interactome mapping
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 667 Hs			1 160
+	Hs
		1069357 HIF1A_HUMAN (2-501): 2.75e-126: 395: 32.11		TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00
+	Hs
		649112 ARNT_HUMAN (2-576): 5.63e-105: 338: 16.72		TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00
+	Hs
		728920 AHR_HUMAN (5-518): 5.16e-91: 303: 20.04		TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00